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TNF Receptor Associated Factor 2 (TRAF2) Antibody Europäischer Partner

Hersteller Abbexa
Kategorie
Typ Antibody Primary
Specific against Human, Mouse, Rat
Isotype IgG
Format Liquid
Applikationen WB, IF, IHC, ICC, ELISA
Menge 100 ug
Host Rabbit
ArtNr abx146871-100
Targets TRAF2, TNF
Konjugat/Tag Unconjugated
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Manufacturers Category
Primary Antibodies
Description
TNF Receptor Associated Factor 2 (TRAF2) Antibody is a Rabbit Polyclonal antibody for the detection of TRAF2.

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined.
Dry Ice
No
Buffer
PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Clonality
Polyclonal
Gene Symbol
TRAF2
Molecular Weight
Observed MW: 54 kDa
Note
This product is for research use only.
OMIM
601895
Purification
Purified by immunogen affinity chromatography.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Target Information
TNF Receptor Associated Factor 2 (TRAF2)
UniProt Entry Name
TRAF2_HUMAN

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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