Antibodies

SEN2 Polyclonal Antibody

Hersteller Abbkine Scientific
Kategorie
Typ Antibody Polyclonal
Specific against Human
Isotype IgG
Applikationen WB, ELISA
Menge 200ul
Host Rabbit
ArtNr ABK-ABP60365-200ul
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Immunogen
Synthesized peptide derived from part region of human SEN2 protein
Applications notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
Purification
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
Formulation
Liquid solution
Concentration
1 mg/ml
Storage buffer
PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage instructions
Stable for one year at -20C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping
Gel pack with blue ice.
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Background
TSEN2 (TRNA Splicing Endonuclease Subunit 2) is a Protein Coding gene. Diseases associated with TSEN2 include Pontocerebellar Hypoplasia Type 2B and Pontocerebellar Hypoplasia, Type 2E. Among its related pathways are Gene Expression and tRNA processing. TSEN2 encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in TSEN2 have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for TSEN2.
Gene ID
80746
Alternative
tRNA-splicing endonuclease subunit Sen2; tRNA-intron endonuclease Sen2; HsSen2
Other info
The antibody detects endogenous levels of SEN2 protein
Accession
Q8NCE0

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Menge: 200ul
Lieferbar: In stock
Listenpreis: 519,44 €
Preis: 519,44 €
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