Fes

Hersteller Abclonal
Kategorie
Typ Antibody Polyclonal
Specific against Human
Applikationen WB, IHC
Protein Familie Tyrosine Kinase
Menge 100ug
Host Rabbit
ArtNr A0612
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
*

DESCRIPTION

Calculated MW
93kDa
Immunogen
A synthetic peptide of human FES
Gene ID
2242
Swiss Prot
P07332
Synonyms
FES; FPS; Tyrosine-protein kinase Fes/Fps; Feline sarcoma/Fujinami avian sarcoma oncogene homolog; Proto-oncogene c-Fes; Proto-oncogene c-Fps; p93c-fes;
Isotype
IgG
Purity
Affinity purification
Storage Buffer
Store at 4? or -20?. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background
This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.
Recommended Dilutions
WB 1:500-1:1000 IHC 1:50-1:100
illustration
Western blot analysis of extracts ofrecombinantprotein, using FES antibody.
Menge: 100ug
Lieferbar: In stock
Listenpreis: 289,30 €
Preis: 289,30 €
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