GAD2

Hersteller Abclonal
Kategorie
Typ Antibody Polyclonal
Specific against Human
Applikationen WB, IF, IHC
Protein Familie Neuroscience
Menge 100ug
Host Rabbit
ArtNr A0779
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Calculated MW
65kDa
Immunogen
A synthetic peptide of human GAD2
Synonyms
GAD2, GAD65
Purity
Affinity purification
Storage Buffer
Store at 4C or -20C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Illustration
Western blot analysis of extracts of Jurkat celllines, using GAD2antibody.
Gene Symbol
GAD2
GeneID (Human)
2572
GeneID
2572
Protein MW
585
SWISS
Q05329
Route
Synthetic Peptide
Menge: 100ug
Lieferbar: In stock
Listenpreis: 289,30 €
Preis: 289,30 €
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