4E-BP1

Hersteller Abclonal
Kategorie
Typ Antibody Polyclonal
Specific against Human
Applikationen WB, FC, IHC
Protein Familie Translational Control
Menge 100ug
Host Rabbit
ArtNr A0787
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
*

DESCRIPTION

Calculated MW
13kDa
Immunogen
Recombinant protein of human EIF4EBP1
Gene ID
1978
Swiss Prot
Q13541
Synonyms
BP-1; 4EBP1; 4E-BP1; PHAS-I;
Isotype
IgG
Purity
Affinity purification
Storage Buffer
Store at 4? or -20?. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Recommended Dilutions
WB 1:500-1:1000 IHC 1:50-1:100 FC 1:20-1:50
illustration
Western blot analysis of extracts of T47D celllines, using EIF4EBP1antibody.
Menge: 100ug
Lieferbar: In stock
Listenpreis: 289,30 €
Preis: 289,30 €
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