CYP3A4

Hersteller Abclonal
Kategorie
Typ Antibody Monoclonal
Specific against Human
Applikationen WB, IHC, ICC
Menge 100ug
Host Mouse
ArtNr A1305
Eclass 6.1 32160702
Eclass 9.0 42030590
Lieferbar
Calculated MW
57kDa
Immunogen
Recombinant Protein of human CYP3A4
Synonyms
HLP, CP33, CP34, CYP3A, NF-25, CYP3A3, P450C3, CYPIIIA3, CYPIIIA4, P450PCN1
Purity
Affinity purification
Storage Buffer
Store at -20C or -80C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist, however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.
Illustration
Western blot analysis of extracts of 293 cell line, using CYP3A4 antibody.
Gene Symbol
CYP3A4
GeneID (Human)
1576
GeneID
1576
Protein MW
503
SWISS
P08684
Route
Recombinant Protein
Menge: 100ug
Lieferbar: In stock
Listenpreis: 366,30 €
Preis: 366,30 €
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