CYP1A1

Hersteller Abclonal
Kategorie
Typ Antibody Monoclonal
Specific against Human
Applikationen WB, IHC
Menge 100ug
Host Mouse
ArtNr A1306
eClass 6.1 32160702
eClass 9.0 42030590
Lieferbar
Calculated MW
58kDa
Immunogen
Recombinant protein of human CYP1A1
Synonyms
AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX
Purity
Affinity purification
Storage Buffer
Store at -20C or -80C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown, however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.
Illustration
Western blot analysis of extracts of Recombinant protein, using CYP1A1 antibody.
Gene Symbol
CYP1A1
GeneID (Human)
1543
GeneID
1543
Protein MW
512
SWISS
P04798
Route
Recombinant Protein
Menge: 100ug
Lieferbar: In stock
Listenpreis: 366,30 €
Preis: 366,30 €
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