FMR1

Hersteller Abclonal
Kategorie
Typ Antibody Monoclonal
Specific against Human
Applikationen WB, IHC, ICC
Menge 100ug
Host Mouse
ArtNr A1414
eClass 6.1 32160702
eClass 9.0 42030590
Lieferbar
Calculated MW
71kDa
Immunogen
Recombinant protein of human FMR1
Synonyms
POF, FMRP, POF1, FRAXA
Purity
Affinity purification
Storage Buffer
Store at -20C or -80C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background
FMR1, also known as POF, FMRP, FRAXA. Entrez Protein: NP_002015. It is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs.
Illustration
Western blot analysis of extracts of K562 cellline, using FMR1 antibody.
Gene Symbol
FMR1
GeneID (Human)
2332
GeneID
2332
Protein MW
632
SWISS
Q06787
Route
Recombinant protein
Menge: 100ug
Lieferbar: In stock
Listenpreis: 366,30 €
Preis: 366,30 €
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