APOA5

Hersteller Abclonal
Kategorie
Typ Antibody Monoclonal
Specific against Human
Applikationen WB, ICC
Menge 100ug
Host Mouse
ArtNr A1424
eClass 6.1 32160702
eClass 9.0 42030590
Lieferbar
Calculated MW
41kDa
Immunogen
Recombinant protein of human APOA5
Synonyms
RAP3, APOAV
Purity
Affinity purification
Storage Buffer
Store at -20C or -80C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background
Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50–70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor- agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Despite these compelling molecular biology data, relatively little is known about ApoA5 protein in human serum.This antibody pair detected recombinant apoa5 protein in sandwich ELISA format and could be potential reagents for the development of clinical diagnostic kits.
Illustration
Western blot analysis of extracts ofRecombinant protein, using APOA5 antibody.
Gene Symbol
APOA5
GeneID (Human)
116519
GeneID
116519
Protein MW
366
SWISS
Q6Q788
Route
Recombinant protein
Menge: 100ug
Lieferbar: In stock
Listenpreis: 366,30 €
Preis: 366,30 €
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