HAMP

Hersteller Abclonal
Kategorie
Typ Antibody Polyclonal
Specific against Human
Applikationen WB, IHC
Menge 200ug
Host Rabbit
ArtNr A1601-200ug
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Calculated MW
9kDa
Immunogen
Recombinant proteinof human HAMP
Synonyms
HEPC, PLTR, HFE2B, LEAP1
Purity
Affinity purification
Storage Buffer
Store at -20C or -80C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background
The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008]
Illustration
Western blot analysis of extracts of MB435cell lines, using HAMP antibody.
Gene Symbol
HAMP
GeneID (Human)
57817
GeneID
57817
Protein MW
84
SWISS
P81172
Route
Recombinant protein
Menge: 200ug
Lieferbar: In stock
Listenpreis: 444,40 €
Preis: 444,40 €
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