Antibodies

C10orf2

Hersteller Abclonal
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse, Rat
Isotype IgG
Applikationen WB, IHC
Menge 200ug
Host Rabbit
ArtNr A5303-200ug
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Background
This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene Symbol
C10orf2
Gene Template
Human
GeneID
56652
Route
Recombinant Protein
SWISS
Q96RR1
Protein MW (aa)
77kDa
Synonyms
PEO, PEO1, SCA8, ATXN8, IOSCA, PEOA3, SANDO, TWINL, MTDPS7,
Purity
Affinity purification
Storage Buffer
Store at -20C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions
WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Illustration
Western blot analysis of extracts of various cell lines, using C10orf2 antibody. Immunofluorescence analysis of A549 cell using C10orf2 antibody. Blue: DAPI for nuclear staining.
Menge: 200ug
Lieferbar: In stock
Listenpreis: 404,00 €
Preis: 404,00 €
lieferbar

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Arbeitsanleitung

A5303-200ug.pdf