BCL6

Hersteller Abclonal
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse
Applikationen WB, FC, IHC
Protein Familie Lymphocyte Signaling
Menge 100ug
Host Rabbit
ArtNr A0477
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
*

DESCRIPTION

Calculated MW
79kDa
Immunogen
A synthetic peptide of human BCL6
Gene ID
604
Swiss Prot
P41182
Synonyms
BCL5; LAZ3; BCL6A; ZNF51; ZBTB27
Isotype
IgG
Purity
Affinity purification
Storage Buffer
Store at 4? or -20?. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
Recommended Dilutions
WB 1:500-1:1000 IHC 1:50-1:100 FC 1:20-1:50
illustration
Western blot analysis of extracts of mouse cerebellum celllines, using BCL6antibody.
Menge: 100ug
Lieferbar: In stock
Listenpreis: 289,30 €
Preis: 289,30 €
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