Cd2ap

Hersteller Abclonal
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse
Applikationen WB
Menge 100ug
Host Rabbit
ArtNr A4569
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
*

DESCRIPTION

Calculated MW
70kDa
Immunogen
Recombinant protein of human Cd2ap
Gene ID
12488
Swiss Prot
Q9Y5K6
Synonyms
CMS;
Isotype
IgG
Purity
Affinity purification
Storage Buffer
Store at -20? or -80?. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background
This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
Recommended Dilutions
WB 1:500-1:2000 IP 1:20-1:50
Menge: 100ug
Lieferbar: In stock
Listenpreis: 289,30 €
Preis: 289,30 €
lieferbar

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