Cathepsin D

Hersteller	Abclonal
Typ	Antibody Polyclonal
Specific against	Human, Mouse, Rat
Applikationen	WB, IF, IHC
Protein Familie	Protein Folding/Stability
Menge	100ug
Host	Rabbit
ArtNr	A0041
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
*	DESCRIPTION
Calculated MW	45kDa
Immunogen	Recombinant Protein of human CTSD
Gene ID	1509
Swiss Prot	P07339
Synonyms	CPSD; CLN10;
Isotype	IgG
Purity	Affinity purification
Storage Buffer	Store at -20? or -80?. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background	This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease.
Recommended Dilutions	WB 1:500-1:2000 IHC 1:50-1:200 IF 1:20-1:50
illustration	Western blot analysis of extracts of HepG2 cell line, using CTSD antibody.

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