Cathepsin D

Hersteller Abclonal
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse, Rat
Applikationen WB, IF, IHC
Protein Familie Protein Folding/Stability
Menge 100ug
Host Rabbit
ArtNr A0041
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
*

DESCRIPTION

Calculated MW
45kDa
Immunogen
Recombinant Protein of human CTSD
Gene ID
1509
Swiss Prot
P07339
Synonyms
CPSD; CLN10;
Isotype
IgG
Purity
Affinity purification
Storage Buffer
Store at -20? or -80?. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background
This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease.
Recommended Dilutions
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:20-1:50
illustration
Western blot analysis of extracts of HepG2 cell line, using CTSD antibody.
Menge: 100ug
Lieferbar: In stock
Listenpreis: 289,30 €
Preis: 289,30 €
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