TLR5

Hersteller Abclonal
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse, Rat
Applikationen WB, IHC
Menge 200ug
Host Rabbit
ArtNr A1721-200ug
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Calculated MW
98kDa
Immunogen
Recombinant protein of human TLR5
Synonyms
FLJ10052, MGC126430, MGC126431, SLEB1, TIL3
Purity
Affinity purification
Storage Buffer
Store at -20C or -80C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background
This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009]
Illustration
Western blot analysis of extracts of HeLacell lines, using TLR5 antibody.
Gene Symbol
TLR5
GeneID (Human)
7100
GeneID
7100
Protein MW
858
SWISS
O60602
Route
Recombinant protein
Menge: 200ug
Lieferbar: In stock
Listenpreis: 444,40 €
Preis: 444,40 €
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