GSTM1

Hersteller Abclonal
Kategorie
Typ Antibody Monoclonal
Specific against Human, Rat
Applikationen WB, FC, IHC
Menge 100ug
Host Mouse
ArtNr A1282
Eclass 6.1 32160702
Eclass 9.0 42030590
Lieferbar
Calculated MW
26kDa
Immunogen
Recombinant proteinof human GSTM1
Synonyms
MU, H-B, GST1, GTH4, GTM1, MU-1, GSTM1-1, MGC26563, GSTM1a-1a, GSTM1b-1b
Purity
Affinity purification
Storage Buffer
Store at -20C or -80C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.
Illustration
Western blot analysis of extracts of variouscell lines, using GSTM1 antibody.
Gene Symbol
GSTM1
GeneID (Human)
2944
GeneID
2944
Protein MW
218
SWISS
P09488
Route
Recombinant Protein
Menge: 100ug
Lieferbar: In stock
Listenpreis: 366,30 €
Preis: 366,30 €
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