Goat anti-TGM2 Antibody

Goat anti-TGM2 Antibody
Principle Name: TGM2
Official Symbol: TGM2
All Name and Symbols: TGM2; transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase); TG2; TGC; C polypeptide; TGase C; TGase-H; protein-glutamine-gamma-glutamyltransferase; tissue transglutaminase; transglutaminase 2; transglutaminase C
Accession Number(s): NP_004604.2
Peptide Sequence: NFESDKLKAVKGFR, is from internal region (near the C Terminus)
Human Gene ID(s): 7052
Non-Human GeneID(s):
Important Comments: This antibody is expected to recognise isoform a (NP_004604.2) only.
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Supplied As: lyophilized powder of 50ug or 100ug IgG; Reconsititute IgG with 100ul or 200ul sterile DI Water and final product will be formulated as 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20C. Minimize freezing and thawing.
Applications: Pep ELISA, WB
Tested Species: Human
Peptide ELISA: antibody detection limit dilution 1 to 128000.
Western Blot: Approx 90kDa band observed in Human Lung lysates and approx 85kDa in lysates of cell line A549 (calculated MW of 77.3kDa according to NP_004604.2). Recommended concentration: 0.03-0.1ug/ml.
Reference(s): Verma A, Wang H, Manavathi B, Fok JY, Mann AP, Kumar R, Mehta K. Increased expression of tissue transglutaminase in pancreatic ductal adenocarcinoma and its implications in drug resistance and metastasis. Cancer Res. 2006 Nov 1; 66(21):10525-33. .PMID: 17079475