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Antibodies

KLRC1 Antibody

Hersteller ProSci
Kategorie
Typ Antibody Primary
Specific against Human
Isotype Ig
Format Liquid
Applikationen WB, FC, IF, IHC-P, Immunostaining
Menge 200ul
Host Rabbit
ArtNr 63-556-200
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Accession #
P26715
Background
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. This protein belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells.
Background References 1
Brooks, A.G., et.al., J. Exp. Med. 185 (4), 795-800 (1997)
Background References 2
Plougastel, B., et.al., Immunogenetics 44 (4), 286-291 (1996)
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Clonality
Polyclonal
Concentration
batch dependent
Conjugate
Unconjugated
Immunogen
This KLRC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-206 amino acids from the C-terminal region of human KLRC1.
Modifications
None
NCBI Gene ID #
3821
NCBI Official Full Name
NKG2-A/NKG2-B type II integral membrane protein
NCBI Official Symbol
KLRC1
NCBI Organism
Homo sapiens
Predicted Molecular Weight
26 kDa
Protein GI #
317373399
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Shipping
blue ice or RT
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Swissprot #
P26715
Tested Applications
WB, IHC-P, IF, Flow
User Note
Optimal dilutions for each application to be determined by the researcher.

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Menge: 200ul
Lieferbar: In stock
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