InVivoMab anti-mouse PSGL-1 (CD162) (Clone: 4RA10)

Hersteller Bio X Cell
Kategorie
Typ Antibody Monoclonal
Specific against Mouse
Clon 4RA10
Isotype IgG1
Applikationen in vivo
Menge 50mg
Host Rat
ArtNr BE0186-50MG
eClass 6.1 32160702
eClass 9.0 42030590
Lieferbar
Quantity options
Description
The 4RA10 monoclonal antibody reacts with mouse P-selectin glycoprotein ligand-1 (PSGL-1) also known as CD162. PSGL-1 is a 230 kDa glycoprotein that is expressed by bone marrow-derived mast and dendritic cells, splenic leukocytes, platelets, peripheral blood neutrophils, and T lymphocytes. PSGL-1 is a ligand for P-selectin (CD62P) and plays roles in leukocyte rolling, the migration of leukocytes into inflamed tissues, and responses to vascular injury. The 4RA10 antibody is reported to block the binding of mouse leukocytes to CD62P and CD62L.
Endotoxin
<2EU/mg (<0.002EU/ug)
Determined by LAL gel clotting assay
Formulation
PBS, pH 7.0
Contains no stabilizers or preservatives
Immunogen
Mouse PSGL-1 human IgG1 fusion protein
Isotype
Rat IgG1, kappa
Molecular Weight
150 kDa
Production
Purified from tissue culture supernatant in an animal free facility
Purification
Protein G
Purity
>95%
Determined by SDS-PAGE
RRID
AB_10950305
Recommended InVivoPure Dilution Buffer
InVivoPure pH 7.0 Dilution Buffer(IP0070)
Recommended Isotype Control(s)
InVivoMAb rat IgG1 isotype control, anti-horseradish peroxidase(BE0088)
Reported Applications
in vivo PSGL-1 blockade
Immunohistochemistry (frozen)
Sterility
0.2 uM filtered
Storage
The antibody solution should be stored at the stock concentration at 4C. Do not freeze.

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Menge: 50mg
Lieferbar: In stock
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