InVivoMab anti-mouse IFNAR-1 (Clone: MAR1-5A3)

Hersteller Bio X Cell
Kategorie
Typ Antibody Monoclonal
Specific against Mouse
Clon MAR1-5A3
Isotype IgG1
Applikationen in vivo
Menge 100mg
Host Mouse
ArtNr BE0241-100MG
eClass 6.1 32160702
eClass 9.0 42030590
Lieferbar
Quantity options
Description
The MAR1-5A3 monoclonal antibody reacts with mouse IFNAR-1 (IFN alpha/beta receptor subunit 1). IFNAR-1 is coexpressed with IFNAR-2 on nearly all cell types and together these two subunits make up the heterodimeric Type I IFN Receptor complex. Type I IFNs (IFN-alpha/beta) bind to the Type I IFN Receptor complex to induce cellular responses including induction of anti-viral, anti-microbial, anti-tumor, and autoimmune responses as well as to regulate the activation, proliferation, and differentiation of many cell types. The MAR1-5A3 antibody has been shown to inhibit Type I IFN receptor signaling in vitro and in vivo.
Endotoxin
<2EU/mg (<0.002EU/ug)
Determined by LAL gel clotting assay
Formulation
PBS, pH 7.0
Contains no stabilizers or preservatives
Immunogen
Extracellular domain of mouse IFNAR-1
Isotype
Mouse IgG1, kappa
Molecular Weight
150 kDa
Production
Purified from tissue culture supernatant in an animal free facility
Purification
Protein G
Purity
>95%
Determined by SDS-PAGE
RRID
AB_2687723
Recommended InVivoPure Dilution Buffer
InVivoPure pH 7.0 Dilution Buffer(IP0070)
Recommended Isotype Control(s)
InVivoMAb mouse IgG1 isotype control, unknown specificity(BE0083)
Reported Applications
in vivo IFNAR-1 blockade
in vitro IFNAR-1 blockade
Western blot
Sterility
0.2 uM filtered
Storage
The antibody solution should be stored at the stock concentration at 4C. Do not freeze.

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Menge: 100mg
Lieferbar: In stock
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