InVivoMab anti-mouse CXCR3 (CD183) (Clone: CXCR3-173)

Hersteller Bio X Cell
Kategorie
Typ Antibody Monoclonal
Specific against Mouse
Clon CXCR3-173
Isotype IgG
Applikationen in vivo
Menge 25mg
Host Armenian Hamster
ArtNr BE0249-25MG
eClass 6.1 32160702
eClass 9.0 42030590
Lieferbar
Quantity options
Description
The CXCR3-173 monoclonal antibody reacts with mouse CXCR3 also known as CD183, a 38 kDa chemokine receptor for CXCL9 (MIG), CXCL10 (IP-10), and CXCL11 (ITAC). CXCR3 is expressed primarily on activated T cells, NK cells, as well as some epithelial cells and endothelial cells. CXCR3 mediates leukocyte trafficking. Binding of chemokine ligands to CXCR3 induces various cellular responses, including integrin activation, cytoskeletal changes and chemotactic migration. The binding of CXCR3-173 to CXCR3 is reported to inhibit receptor binding of CXCL10 and CXCL11 but not CXCL9.
Endotoxin
<2EU/mg (<0.002EU/ug)
Determined by LAL gel clotting assay
Formulation
PBS, pH 7.0
Contains no stabilizers or preservatives
Immunogen
Peptide consisting of amino acids 1-37 of mouse CXCR3
Isotype
Armenian Hamster IgG
Molecular Weight
150 kDa
Production
Purified from tissue culture supernatant in an animal free facility
Purification
Protein G
Purity
>95%
Determined by SDS-PAGE
RRID
AB_2687730
Recommended InVivoPure Dilution Buffer
InVivoPure pH 7.0 Dilution Buffer(IP0070)
Recommended Isotype Control(s)
InVivoMAb polyclonal Armenian hamster IgG(BE0091)
Reported Applications
in vivo CXCR3 neutralization
Flow cytometry
Sterility
0.2 uM filtered
Storage
The antibody solution should be stored at the stock concentration at 4C. Do not freeze.

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Menge: 25mg
Lieferbar: In stock
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