Hersteller |
IchorBio
|
Kategorie |
|
Typ |
Antibody |
Specific against |
Mouse |
Clon |
PK136 |
Isotype |
IgG2a Kappa |
Applikationen |
WB, FC, IP, IHC, Blocking |
Menge |
50mg |
Host |
Mouse |
ArtNr |
ICH1128-50MG |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Manufacturers Product Category |
Low Endotoxin, anti-mouse |
Target Information |
NK1.1 |
Isotype Information |
Mouse IgG2a Kappa |
Purification method |
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
Antigen Distribution |
Mouse NK cells. Endogenous and interferon induced NK cells. Not present on cytotoxic T-cells and Con A stimulated blast cells. May be present on a certain subset of cytotoxic T-cells strains A, AKR, BALB/C, BALB.H-2b, CBA, C3H, DBA/2, 124 were negative using PK136. |
Background |
NK-1.1 surface antigen, also known as CD161b/CD161c, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers. |
Immunogen |
NK-1+ cells from mouse spleen and bone marrow |
Concentration |
1.0 - 5.0 mg/ml |
Formulation |
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. |
Endotoxin |
≤ 1.0 EU/mg as determined by the LAL method |
Aggregation |
Aggregation level ≤ 5% |
Storage |
anti-NK1.1 In Vivo Antibody - Low Endotoxin (PK136) is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
Application Notes |
Each investigator should determine their own optimal working dilution for specific applications. |
Use |
Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.