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Anti-Human TRAIL R3 - 25 µg

Anti-Human TRAIL R3 - 25 µg

ArtNr	LEIN-T470-25ug
Hersteller	Leinco Technologies
Menge	25 ug
Quantity options	100 ug 25 ug
Kategorie	Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Primary
Applikationen	WB, IHC
Specific against	Human (Homo sapiens)
Host	Caprine
Citations	1. Fornace Jr., AJ. et al. (1999) Oncogene 18: 4153 2. Büchler, MW. et al. (2001) Anticancer Res. 21: 3153 3. Smith, CA. et al. (1997) J Exp Med. 186: 1165
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Applications	IHC FFPE, WB
Manufacturer - Category	Polyclonal Antibodies>Growth Factors & Cytokines
Manufacturer - Targets	TRAIL R3
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Product Description	TNF-related apoptosis-inducing ligand receptor 3 (TRAIL R3) is an antagonist decoy receptor1 that can inhibit TRAIL-induced apoptosis.2 TRAIL R3 is a plasma membrane-bound protein capable of high affinity interaction with the TRAIL ligand.3
Background	TNF-related apoptosis-inducing ligand receptor 3 (TRAIL R3) is an antagonist decoy receptor¹ that can inhibit TRAIL-induced apoptosis.² TRAIL R3 is a plasma membrane-bound protein capable of high affinity interaction with the TRAIL ligand.³
Other Applications Reported In Literature	IHC (NBF/Par.): This antibody should give satisfactory staining results when used at a concentration of 10 µg/ml. The recommended secondary antibody for IHC is PN:G505. For chromogenic detection with high signal and low background use PN:D100 or PN:K107.
PubMed	TRAIL R3
Manufacturer - Specificity	Goat Anti-Human TNF-Related Apoptosis-Inducing Ligand Receptor 3 (TRAIL R3) recognizes Human TRAIL R3. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.
RRID	AB_2831970
Formulation	This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.
Endotoxin Level	< 0.1 EU/µg as determined by the LAL method
Immunogen	NS0-Derived Recombinant Human TRAIL R3 Extracellular Domain
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Polyclonal Antibody, TNF-Related Apoptosis-Inducing Ligand Receptor 3, TRID, TNFRSF10C, CD263, DCR1, LIT, MGC149501, MGC149502, TRAIL R3, Human TRAIL R3, Anti-Human TRAIL R3, Antagonist decoy receptor for TRAIL/Apo-2L, CD263 antigen, CD263, cytotoxic TRAIL receptor-3, DcR1, DCR1MGC149502, Decoy receptor 1, Decoy TRAIL receptor without death domain, LITMGC149501, Lymphocyte inhibitor of TRAIL, TNFRSF10C, TRAIL R3, TRAIL receptor 3, TRAIL receptor without an intracellular domain, TRAILR3, TRAIL-R3, TRAILR3TNF-related apoptosis-inducing ligand receptor 3, TRIDDCR1-TNFR, tumor necrosis factor receptor superfamily member 10C, tumor necrosis factor receptor superfamily, member 10c, decoy without anintracellular domain

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LEIN-T470-25ug-safety-datasheet.pdf