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MAPK14 Peptide (AAP30459)

ArtNr AAP30459
Hersteller AVIVA Systems Biology
Menge 100 ug
Kategorie
Typ Peptides
Format Lyophilized
Applikationen WB, IHC
Specific against other
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products MAPK14
Lieferbar
Molecular Weight
41kDa
Description
This is a synthetic peptide designed for use in combination with anti-MAPK14 antibody (Catalog #: AVARP06004_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Gene symbol
MAPK14
Protein size
360
Product format
Lyophilized powder
Reconstitution and storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Partner proteins
CDC25B, NCF1C, ATF2, BCL2, CDC25B, CDC25C, CDX2, CREB1, CSNK2A2, CSNK2B, DDIT3, DUSP1, DUSP10, DUSP16, DUSP2, DUSP22, DUSP4, DUSP7, DUSP9, DYRK1B, EEA1, EEF2K, EIF4EBP1, ELK1, ELK3, ESR1, FAM48A, FKBP8, FLNA, GADD45A, GMFB, GRB2, HNF4A, HSF4, HTRA2, IRAK1, JDP2, JUNB, KRT18, KRT8, MAFA, MAP2K1, MAP2K3, MAP2K4, MAP2K6, MAP3K7, MAPK1, MAPK3, MAPK8, MAPKAPK2, MAPKAPK3, MAPKAPK5, MAX, MBP, MEF2A, MEF2C, MITF, MKNK1, MKNK2, NCF1, NCOA3, NFATC1, NFATC4, NUP153, PLA2G4A, PML, PPARGC1A, PTPN7, RET, RPS6KA4, SCN8A, SHC1, SLC9A1, SMAD3, SMAD7, SPAG9, STAT1, STAT4, STK39, TAB1, TRAF6, ZFP36L1, ZFYVE20, ZNHIT1, AKT1, ATF2, ATF2, ATF2, ATF2, CDC25A, CDC25B, CDC25C, CSNK2A1, DDIT3, DUSP1, DUSP10, DUSP10, DUSP16, DUSP4, DUSP6, DYRK1B, EGFR, ELK1, ELK1, ELK4, ELK4, ETV1, FUBP1, GMFB, HTRA2, JUN, KARS, KRT8, MAP2K3, MAP2K3, MAP2K6, MAP2K7, MAPK1, MAPK14, MAPK3, MAPKAPK2, MAPKAPK3, MEF2A, MKNK1, MKNK1, PLCB2, RPS6KA3, RPS6KA4, RPS6KA5, Rps6kb1, SLC12A2, SMAD7, SPAG9, STK39, TAB1, TAB1, TGFBR1, ZFP36L1
Description of target
MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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