Antibodies

FAS Polyclonal Antibody

Hersteller Biomatik
Kategorie
Typ Antibody Polyclonal
Specific against Human
Applikationen WB, IHC, ELISA
Menge 100ug
Host Rabbit
ArtNr BM-CAC07062-100ug
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Immunogen
Recombinant human Tumor necrosis factor receptor superfamily member 6 protein (26-171AA)
Conjugate
Unconjugated
Alternative Names
Apo-1 antigen Apoptosis-mediating surface antigen FAS FASLG receptor CD_antigen=CD95
UniProt ID
P25445
Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Storage Instructions
Aliquot and store at -20C. Minimize freezing and thawing.
Expiry Date
1 year
Shipping Condition
Blue ice
Comment
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Restriction
For research use only. Not for diagnostic procedures.
Menge: 100ug
Lieferbar: In stock
Listenpreis: 362,11 €
Preis: 362,11 €
lieferbar

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