PPARG Polyclonal Antibody

Recombinant human Peroxisome proliferator-activated receptor gamma protein (1-477AA)

PPAR-gamma, Nuclear receptor subfamily 1 group C member 3, PPARG, NR1C3

Caprylic Acid Ammonium Sulfate Precipitation Purified

1 year

Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses.