CDKN1A Polyclonal Antibody

Hersteller Biomatik
Kategorie Produkte / Antibody / Research Area / Oncology / Bladder Cancer / Testicular & Prostate Cancer / Skin Cancer / Lung Cancer / Breast Cancer / Colorectal Cancer
Typ Antibody Polyclonal
Specific against Human
Menge 50ug
Host Rabbit
ArtNr BM-CAC08304-50ug
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Clonality
Polyclonal
Isotype info
Recombinant Human Cyclin-dependent kinase inhibitor 1 protein (2-164AA)
Immunogen
ELISA, IHC, IF; Recommended dilution: IHC:1:1000-1:2000, IF:1:200-1:500
Conjugation
Unconjugated
Alternative Names
CDK-interacting protein 1, Melanoma differentiation-associated protein 6, p21, CDKN1A, CAP20, CDKN1, CIP1, MDA6, PIC1, SDI1, WAF1
UniProt ID
P38936
Purification
>95%, Protein G purified
Storage
-20°C
Expiry Date
1 year
Shipping Condition
Ice packs
Comments
Conjugation service and the corresponding secondary antibody are available.
Technical Notes
May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.
Restriction
For research use only. Not for diagnostic procedures.
Menge: 50ug
Lieferbar: In stock
Listenpreis: 218,49 €
Preis: 218,49 €
lieferbar

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