Antibodies

FKBP6 Polyclonal Antibody

Hersteller Biomatik
Kategorie
Typ Antibody Polyclonal
Specific against Human
Menge 100ug
Host Rabbit
ArtNr BM-CAC08441-100ug
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Clonality
Polyclonal
Isotype info
Recombinant human Inactive peptidyl-prolyl cis-trans isomerase FKBP6 protein (101-327AA)
Immunogen
ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
Conjugation
Unconjugated
Alternative Names
Inactive peptidyl-prolyl cis-trans isomerase FKBP6, Inactive PPIase FKBP6, 36 kDa FK506-binding protein, 36 kDa FKBP, FKBP-36, FK506-binding protein 6, FKBP-6, Immunophilin FKBP36, FKBP6, FKBP36
UniProt ID
O75344
Purification
>95%, Protein G purified
Storage
-20°C
Expiry Date
1 year
Shipping Condition
Ice packs
Comments
Conjugation service and the corresponding secondary antibody are available.
Technical Notes
Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes.
Restriction
For research use only. Not for diagnostic procedures.
Menge: 100ug
Lieferbar: In stock
Listenpreis: 332,79 €
Preis: 332,79 €
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