Hersteller |
Biomatik |
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human |
Menge |
50ug |
Host |
Rabbit |
ArtNr |
BM-CAC08489-50ug |
Eclass 6.1 |
32160702 |
Eclass 9.0 |
32160702 |
Lieferbar |
|
Clonality |
Polyclonal |
Isotype info |
Recombinant human Beta-adrenergic receptor kinase 1 protein (2-221AA) |
Immunogen |
ELISA, IHC; Recommended dilution: IHC:1:20-1:200 |
Conjugation |
Unconjugated |
Alternative Names |
G-protein coupled receptor kinase 2, ADRBK1, BARK, BARK1, GRK2 |
UniProt ID |
P25098 |
Purification |
>95%, Protein G purified |
Storage |
-20°C |
Expiry Date |
1 year |
Shipping Condition |
Ice packs |
Comments |
Conjugation service and the corresponding secondary antibody are available. |
Technical Notes |
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. |
Restriction |
For research use only. Not for diagnostic procedures. |