Antibodies

KEAP1 Polyclonal Antibody

Hersteller Biomatik
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse
Applikationen WB, IHC, ELISA
Menge 100ug
Host Rabbit
ArtNr BM-CAC07039-100ug
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Immunogen
Recombinant human Kelch-like ECH-associated protein 1 protein (1-624AA)
Conjugate
Unconjugated
Alternative Names
Kelch-like ECH-associated protein 1, Cytosolic inhibitor of Nrf2, INrf2, Kelch-like protein 19, KEAP1, INRF2, KIAA0132, KLHL19
UniProt ID
Q14145
Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Storage Instructions
Aliquot and store at -20C. Minimize freezing and thawing.
Expiry Date
1 year
Shipping Condition
Blue ice
Comment
Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
Restriction
For research use only. Not for diagnostic procedures.
Menge: 100ug
Lieferbar: In stock
Listenpreis: 330,25 €
Preis: 330,25 €
lieferbar

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