Antibodies

CDH5 Polyclonal Antibody

Hersteller Biomatik
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse
Applikationen WB, IF, ELISA
Menge 50ug
Host Rabbit
ArtNr BM-CAC08147-50ug
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Immunogen
Recombinant Human Cadherin-5 protein (349-569AA)
Conjugate
Unconjugated
Alternative Names
Cadherin-5, 7B4 antigen, Vascular endothelial cadherin, VE-cadherin, CD144, CDH5
UniProt ID
P33151
Purification
Protein G purified, >95%
Storage Instructions
Aliquot and store at -20C. Minimize freezing and thawing.
Expiry Date
1 year
Shipping Condition
Blue ice
Comment
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.
Restriction
For research use only. Not for diagnostic procedures.
Menge: 50ug
Lieferbar: In stock
Listenpreis: 215,65 €
Rabatt: -10,0%
Preis: 194,09 €
Sie sparen: 21,57 €
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