|
Hersteller |
Biomatik
|
|
Kategorie |
|
|
Typ |
Antibody Polyclonal |
|
Specific against |
Human, Mouse |
|
Menge |
50ug |
|
Host |
Rabbit |
|
ArtNr |
BM-CAC08351-50ug |
|
eClass 6.1 |
32160702 |
|
eClass 9.0 |
32160702 |
|
Lieferbar |
 |
| Clonality |
Polyclonal |
| Isotype info |
Recombinant human Cysteinyl leukotriene receptor 1 protein (298-337AA) |
| Immunogen |
ELISA, WB, IHC, IF; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Conjugation |
Unconjugated |
| Alternative Names |
Cysteinyl leukotriene receptor 1, CysLTR1, Cysteinyl leukotriene D4 receptor, LTD4 receptor, G-protein coupled receptor HG55, HMTMF81, CYSLTR1, CYSLT1 |
| UniProt ID |
Q9Y271 |
| Purification |
>95%, Protein G purified |
| Storage |
-20°C |
| Expiry Date |
1 year |
| Shipping Condition |
Ice packs |
| Comments |
Conjugation service and the corresponding secondary antibody are available. |
| Technical Notes |
Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4. |
| Restriction |
For research use only. Not for diagnostic procedures. |
