ACTN4 Polyclonal Antibody

Hersteller Biomatik
Kategorie Produkte / Antibody / Research Area / Oncology / Bladder Cancer
Typ Antibody Polyclonal
Specific against Human, Mouse
Menge 100ug
Host Rabbit
ArtNr BM-CAC08425-100ug
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Clonality
Polyclonal
Isotype info
Recombinant Human Alpha-actinin-4 protein (6-277AA)
Immunogen
ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200
Conjugation
Unconjugated
Alternative Names
Alpha-actinin-4Curated, Non-muscle alpha-actinin 4, ACTN4
UniProt ID
O43707
Purification
>95%, Protein G purified
Storage
-20°C
Expiry Date
1 year
Shipping Condition
Ice packs
Comments
Conjugation service and the corresponding secondary antibody are available.
Technical Notes
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (PubMed:15772161). Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions (By similarity). May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA (PubMed:22351778).
Restriction
For research use only. Not for diagnostic procedures.
Menge: 100ug
Lieferbar: In stock
Listenpreis: 332,24 €
Preis: 332,24 €
lieferbar

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