LIN7A Polyclonal Antibody

Hersteller Biomatik
Kategorie
Typ Antibody Polyclonal
Specific against Human, Mouse, Carp
Menge 50ug
Host Rabbit
ArtNr BM-CAC08592-50ug
Eclass 6.1 32160702
Eclass 9.0 32160702
Lieferbar
Clonality
Polyclonal
Isotype info
Recombinant human Protein lin-7 homolog A protein (1-233AA)
Immunogen
ELISA, WB; Recommended dilution: WB:1:1000-1:5000
Conjugation
Unconjugated
Alternative Names
Protein lin-7 homolog A, Lin-7A, hLin-7, Mammalian lin-seven protein 1, MALS-1, Tax interaction protein 33, TIP-33, Vertebrate lin-7 homolog 1, Veli-1, LIN7A, MALS1, VELI1
UniProt ID
O14910
Purification
>95%, Protein G purified
Storage
-20°C
Expiry Date
1 year
Shipping Condition
Ice packs
Comments
Conjugation service and the corresponding secondary antibody are available.
Technical Notes
Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
Restriction
For research use only. Not for diagnostic procedures.
Menge: 50ug
Lieferbar: In stock
Listenpreis: 239,93 €
Preis: 239,93 €
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