Anti-Dystrophin DMD Antibody

ArtNr	BOS-A00069
Hersteller	Boster
Menge	100 ul
Quantity options	100 ul 100 ul
Kategorie	Metabolism Glucose Homeostasis Immunohistochemistry Western Blot Immunofluorescence Immunocytochemistry Immunochemistry
Format	Liquid
Applikationen	WB, IF, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Alias	Dystrophin,DMD
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	426750 MW
Clonality	Polyclonal
Application Details	WB: 1:200-1:2000 IHC: 1:50-1:200 ICC/IF: 1:50-1:200
Gene Name	DMD
Gene Full Name	Dystrophin
Immunogen	Recombinant fusion protein of human Dystrophin(NP_003997.2).
Contents	Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Concentration	1 mg/ml
Protein Name	Dystrophin
Protein Function	Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin- associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission.
Subcellular Localization	Cell membrane, sarcolemma
Description	Boster Bio Anti-Dystrophin DMD Antibody catalog # A00069. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma. Expressed in brain, muscle, kidney, lung and testis. Isoform 5 is expressed in heart, brain, liver, testis and hepatoma cells. Most tissues contain transcripts of multiple isoforms, however only isoform 5 is detected in heart and liver.

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Arbeitsanleitung (Data Sheet) anfordern

BOS-A00069-datasheet.pdf

BOS-A00069-safety-datasheet.pdf