Anti-PPAR Gamma (phospho-S112) PPARG Antibody

Primary Antibodies

57620 MW

WB: 1:500-1:1000
IHC: 1:50-1:200

Peroxisome proliferator-activated receptor gamma

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

1 mg/ml

Nuclear receptor that binds peroxisome proliferators
such as hypolipidemic drugs and fatty acids. Once activated by a
ligand, the nuclear receptor binds to DNA specific PPAR response
elements (PPRE) and modulates the transcription of its target
genes, such as acyl-CoA oxidase. It therefore controls the
peroxisomal beta-oxidation pathway of fatty acids. Key regulator
of adipocyte differentiation and glucose homeostasis. ARF6 acts as
a key regulator of the tissue-specific adipocyte P2 (aP2)
enhancer. Acts as a critical regulator of gut homeostasis by
suppressing NF-kappa-B-mediated proinflammatory responses. Plays a
role in the regulation of cardiovascular circadian rhythms by
regulating the transcription of ARNTL/BMAL1 in the blood vessels
(By similarity).

Boster Bio Anti-PPAR Gamma (phospho-S112) PPARG Antibody catalog # A00449S112. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.