Anti-RNase III Drosha Antibody

Hersteller Boster
Kategorie
Typ Antibody
Specific against other
Applikationen WB, IHC
Menge 100ul
Host Rabbit
ArtNr BOS-A00111
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Gene name
DROSHA
Clonality
Polyclonal
Conjugate
No
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Description
Polyclonal antibody for DROSHA detection. Host: Rabbit.Size: 100ul. Tested applications: IHC. Reactive species: Human. DROSHA information: Molecular Weight: 159316 MW; Subcellular Localization: Nucleus . Nucleus, nucleolus . A fraction is translocated to the nucleolus during the S phase of the cell cycle. Localized in GW bodies (GWBs), also known as P-bodies; Tissue Specificity: Ubiquitous.
Uniprot ID
Q9NRR4
Immunogen
Synthesized peptide derived from the Internal region of human RNase III Drosha.
Purification
Immunogen affinity purified
Storage
Store at -20° C for one year, at 4° C for one month. We suggest the antibody be aliquotted into small vials and stored frozen at -20° C upon receiving. Avoid repeated freezing and thawing.
Application details
WB, 1:500-1:2000
IHC-P, 1:100-1:300
Reactivity
Human, Mouse
Research category
|epigenetics and nuclear signaling|dna / rna|rna processing|rnai| epigenetics and nuclear signaling|dicer|chip'ing antibodies|nuclear signaling pathways|nuclear receptors|nuclear pore complex
Synonyms
Ribonuclease 3, 3.1.26.3 , Protein Drosha , Ribonuclease III, RNase III, p241, DROSHA, RN3, RNASE3L, RNASEN,
Molecular weight
159316 MW
Protein function
Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA- ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double- strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies. .
Menge: 100ul
Lieferbar: In stock
Listenpreis: 386,89 €
Preis: 386,89 €
lieferbar

Vergleichen

Angebot anfordern

Fragen zum Produkt?
 
Schließen