Antibodies

Anti-FADD Antibody

Hersteller Boster
Kategorie
Typ Antibody
Specific against other
Applikationen WB
Menge 100ul
Host Rabbit
ArtNr BOS-A00237-1
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Gene name
FADD
Clonality
Polyclonal
Conjugate
No
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Description
Polyclonal antibody for FADD detection. Host: Rabbit.Size: 100ul. Tested applications: WB. Reactive species: Mouse. FADD information: Molecular Weight: 23279 MW; Tissue Specificity: Expressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes.
Uniprot ID
Q13158
Immunogen
Synthesized peptide derived from mouse FADD around the non-phosphorylation site of S191.
Purification
Immunogen affinity purified
Storage
Store at -20° C for one year, at 4° C for one month. We suggest the antibody be aliquotted into small vials and stored frozen at -20° C upon receiving. Avoid repeated freezing and thawing.
Application details
WB, 1:500-1:2000
Reactivity
Mouse
Research category
|cell biology|apoptosis|intracellular|associated proteins| cancer|invasion/microenvironment|death receptors & ligands|fadd|cell death|receptors|necroptosis
Synonyms
FAS-associated death domain protein, FAS-associating death domain-containing protein, Growth-inhibiting gene 3 protein, Mediator of receptor induced toxicity, Protein FADD, FADD, MORT1, GIG3,
Molecular weight
23279 MW
Protein function
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. .
Menge: 100ul
Lieferbar: Out of stock
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