Anti-FGF23 Antibody Picoband™

Primary Antibodies, Rabbit Polyclonal Antibodies

Boster Bio Anti-FGF23 Antibody Picoband™ catalog # A00478-3. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat.

Fibroblast growth factor 23orFGF23is aproteinthat in humans is encoded by theFGF23gene. This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC).

Western blot, 0.1-0.5μg/ml
ELISA, 0.1-0.5μg/ml

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

E. coli-derived rat FGF23 recombinant protein (Position: Y25-V251).

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

fibroblast growth factor 23

Regulator of phosphate homeostasis (By similarity). Inhibits renal tubular phosphate transport by reducing SLC34A1 levels (By similarity). Regulator of vitamin-D metabolism (By similarity). Negatively regulates osteoblasts differentiation and matrix mineralization (By similarity). Acts directly on the parathyroid to decrease PTH secretion. Upregulates EGR1 expression in the presence of KL.

Expressed in the parathyroid.