Anti-Human Neurexin 1 DyLight® 550 conjugated NRXN1 Antibody

Primary Antibodies, Rabbit Polyclonal Antibodies

Boster Bio Anti-Human Neurexin 1 DyLight® 550 conjugated NRXN1 Antibody catalog # A01490-Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.

Neurexin-1-alpha is a protein that in humans is encoded by the NRXN1 gene. This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca (2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3, 000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia.

Flow Cytometry, 1-3μg/1x10⁶ cells

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

E. coli-derived human Neurexin 1 recombinant protein (Position: D141-E294).

At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling. May play a role in angiogenesis (By similarity)..