Antibodies

Anti-Human RAB27A DyLight 488 conjugated Antibody

Hersteller Boster
Kategorie
Typ Antibody Primary
Specific against other
Isotype IgG
Format Liquid
Applikationen FC
Menge 100ug/vial
Host Rabbit
ArtNr BOS-A01608-Dyl488
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Clonality
Polyclonal
Description short
Rabbit IgG Polyclonal Anti-Human RAB27A Antibody DyLight 488 Conjugated, Flow Validated.
Specificity
No cross reactivity with other proteins.
Reactivity
Reacts with: human
Application details
Flow Cytometry|1-3ug/1x106 cells
Notes
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Immunogen
E. coli-derived human RAB27A recombinant protein (Position: L98-K216).
Contents
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Purification
Immunogen affinity purified.
Storage
At 2-8C for one year. Protect from light. Do not freeze.
Background
Ras-related protein Rab-27A is a protein that in humans is encoded by the RAB27A gene. The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
Reference
1. Aksu, G., Kutukculer, N., Genel, F., Vergin, C., Omowaire, B. Griscelli syndrome without hemophagocytosis in an eleven-year-old girl: expanding the phenotypic spectrum ofRab27A mutations in humans. Am. J. Med. Genet. 116A: 329-333, 2003.
2. Kuroda, T. S., Fukuda, M., Ariga, H., Mikoshiba, K. The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain. J. Biol. Chem. 277: 9212-9218, 2002.
Gene Name
RAB27A
Protein Name
Ras-related protein Rab-27A
Gene Full Name
RAB27A, member RAS oncogene family
Synonyms
Ras-related protein Rab-27A; Rab-27; GTP-binding protein Ram; RAB27A; RAB27
Uniprot ID
P51159
Entrez GeneID
5873
Menge: 100ug/vial
Lieferbar: In stock
Listenpreis: 290,00 €
Preis: 290,00 €
lieferbar

Vergleichen

Angebot anfordern

Fragen zum Produkt?
 
Schließen