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Anti-KCNN4 Antibody Picoband™

Anti-KCNN4 Antibody Picoband™

Hersteller	Boster
Kategorie	Neuroscience Molecular Targets for Neuroscience Antibodies Western Blot ELISA Primary Antibodies
Typ	Antibody Primary
Specific against	Human, Mouse, Rat
Isotype	IgG
Format	Lyophilized
Applikationen	WB, ELISA
Menge	100 ug/vial
Host	Rabbit
ArtNr	BOS-A01936-2
eClass 6.1	32160702
eClass 9.0	32160702
Lieferbar
Manufacturers Product Category	Primary Antibodies, Rabbit Polyclonal Antibodies
Manufacturers Research Category	Cell Biology, Neuroscience, Neurotransmission, Potassium Channels, Receptors / Channels
Short Description	Boster Bio Anti-KCNN4 Antibody Picoband™ catalog # A01936-2. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-KCNN4 Antibody Picoband™ catalog # A01936-2. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Background	Intermediate conductance calcium-activated potassium channel protein 1 (KCNN4, Kca3.1) is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. KCNN4 may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.
Gene Name	KCNN4
Application Details	Western blot, 0.1-0.5μg/ml Direct ELISA, 0.1-0.5μg/ml
Clonality	Polyclonal
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Contents	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na₂HPO₄, 0.05mg NaN₃.
Immunogen	E. coli-derived human KCNN4 recombinant protein (Position: K309-Q364).
Cross-reactivity	No cross-reactivity with other proteins.
Storage	Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Gene Full Name	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
Molecular Weight	48 kDa
Protein Function	Forms a voltage-independent potassium channel that is activated by intracellular calcium (PubMed:26148990). Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin (PubMed:17157250, PubMed:18796614).
Subcellular Localization	Cell membrane.
Tissue Specificity	Widely expressed in non-excitable tissues.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ug/vial

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Lieferung vsl. bis 30.05.2024

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