Anti-GPR120 FFAR4 Antibody

Boster Bio Anti-GPR120 FFAR4 Antibody (Catalog# A19859). Tested in WB, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat.

FFAR4

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Western Blot, 1:500 - 1:2000
Immunofluorescence, 1:200 - 1:1000
ELISA, 1:5000
Not yet tested in other applications.

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Free fatty acid receptor 4

Receptor for medium and long-chain free fatty acids (FFAs). Signals via a G (q)/G (11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti- inflammatory effects, particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1-dependent effect, but independent of the G (q)/G (11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage- induced tissue inflammation. May mediate the taste of fatty acids. Mediates FFA-induced inhibition of apoptosis in enteroendocrine cells. May play a role in the regulation of adipocyte development and differentiation.

Abundant expression in the intestinal tract. Highly expressed in adipose tissue, small intestine and pancreas.