Antibodies

Anti-RAD51L3 Antibody

Hersteller Boster
Kategorie
Typ Antibody
Specific against other
Applikationen WB
Menge 100ug/vial
Host Rabbit
ArtNr BOS-A20020
eClass 6.1 32160702
eClass 9.0 32160702
Lieferbar
Gene name
RAD51D
Clonality
Polyclonal
Conjugate
No
Contents
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Description
Polyclonal antibody for RAD51D detection. Host: Rabbit.Size: 100ug/vial. Tested applications: WB. Reactive species: Human. RAD51D information: Molecular Weight: 35049 MW; Subcellular Localization: Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, telomere; Tissue Specificity: Expressed in colon, prostate, spleen, testis, ovary, thymus and small intestine. Weakly expressed in leukocytes.
Uniprot ID
O75771
Immunogen
A peptide derived from human RAD51L3. Immunogen sequence location: 131-180
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Storage
At -20° C for one year. After reconstitution, at 4° C for one month. It can also be aliquotted and stored frozen at -20° C for a longer time.Avoid repeated freezing and thawing.
Application details
User need to optimize the dilution ratio for this antibody
Reactivity
Human
Research category
|epigenetics and nuclear signaling|dna / rna|dna damage & repair|homologous recomb.
Synonyms
DNA repair protein RAD51 homolog 4, R51H3, RAD51 homolog D, RAD51-like protein 3, TRAD, RAD51D, RAD51L3,
Molecular weight
35049 MW
Protein function
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single- stranded DNA (ssDNA) and has DNA-dependent ATPase activity. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single- stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM. .
Menge: 100ug/vial
Lieferbar: In stock
Listenpreis: 386,89 €
Preis: 386,89 €
lieferbar

Vergleichen

Angebot anfordern

Fragen zum Produkt?
 
Schließen