Anti-MRGX1 MRGPRX1 Antibody

Primary Antibodies

Boster Bio Anti-MRGX1 MRGPRX1 Antibody (Catalog# A30840). Tested in WB, IF, ICC, ELISA applications. This antibody reacts with Human, Rat, Mouse.

MRGPRX1

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Western Blot, 1:500 - 1:2000
Immunofluorescence, 1:200 - 1:1000
ELISA, 1:5000
Not yet tested in other applications.

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Mas-related G-protein coupled receptor member X1

Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22) (PubMed:26582731). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G (alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine- induced itch, in a histamine-independent manner.

Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.