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Anti-MRGX1 MRGPRX1 Antibody

Anti-MRGX1 MRGPRX1 Antibody

ArtNr	BOS-A30840
Hersteller	Boster
Menge	100 ul
Kategorie	Food Safety Histamines Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Typ	Antibody
Format	Liquid
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	MRGPRX1,MRGX1,SNSR3,SNSR4,Mas-related G-protein coupled receptor member X1,Sensory neuron-specific G-protein coupled receptor 3/4
Lieferbar
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Molecular Weight	36250 MW
Clonality	Polyclonal
Application Details	WB 1:500-2000 IHC 1:50-300
Gene Name	MRGPRX1
Gene Full Name	Mas-related G-protein coupled receptor member X1
Immunogen	A peptide derived from human MRGX1. Immunogen sequence location: 271 - 320
Contents	PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	G Protein Signaling, Signal Transduction, Signaling Pathway
Protein Function	Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22) (PubMed:26582731). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G (alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine- induced itch, in a histamine-independent manner.
Subcellular Localization	Cell membrane; Multi-pass membrane protein.
Description	Boster Bio Anti-MRGX1 MRGPRX1 Antibody (Catalog# A30840). Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.
Short Description	Boster Bio Anti-MRGX1 MRGPRX1 Antibody (Catalog# A30840). Tested in WB, IF, ICC, ELISA applications. This antibody reacts with Human, Rat, Mouse.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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BOS-A30840-datasheet.pdf

BOS-A30840-safety-datasheet.pdf