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Anti-MIF Rabbit Monoclonal Antibody Europäischer Partner

ArtNr BOS-M00411
Hersteller Boster
Menge 100 ul
Quantity options 100 ul 30 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, FC, IP
Clon ABAG-13
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Sensitivity <20 pg/ml
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Macrophage migration inhibitory factor,MIF,5.3.2.1,Glycosylation-inhibiting factor,GIF,L-dopachrome isomerase,L-dopachrome tautomerase,5.3.3.12,Phenylpyruvate tautomerase,MIF,GLIF,MMIF
Lieferbar
Manufacturer - Category
Primary Antibodies, Rabbit Monoclonal Antibodies
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular weight
12 kDa
Calculated Molecular weight
12476 MW
Clonality
Monoclonal
Application Details
WB 1:500-2000
IP 1:20
FC 1:20
Gene Name
MIF
Gene Full Name
Macrophage migration inhibitory factor
Immunogen
A synthesized peptide derived from human MIF
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Purification
Affinity-chromatography
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration
0.5mg/ml
Manufacturer - Research Category
Immunology, Innate Immunity, Macrophage/Inflammation
Protein Name
T-cell surface glycoprotein CD4
Protein Function
Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti- inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.
Subcellular Localization
Secreted. Cytoplasm. Does not have a cleavable signal sequence and is secreted via a specialized, non- classical pathway. Secreted by macrophages upon stimulation by bacterial lipopolysaccharide (LPS), or by M.tuberculosis antigens.
Description
Boster Bio Anti-MIF Rabbit Monoclonal Antibody catalog # M00411. Tested in WB, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity
Widely expressed in adult and fetal tissues; very highly expressed in tumor cell lines such as HeLaS3, K-562, HL-60, SW480, A-549 and G-361; highly expressed in heart, peripheral blood lymphocytes, liver, pancreas, spleen, thymus, prostate, ovary, uterus, placenta, testis, esophagus, stomach and throughout the intestinal tract; not detectable in brain.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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Lieferung vsl. bis 04.12.2025 

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