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Anti-GRK2 ADRBK1 Rabbit Monoclonal Antibody

Anti-GRK2 ADRBK1 Rabbit Monoclonal Antibody

ArtNr	BOS-M01473
Hersteller	Boster
Menge	100 ul
Quantity options	100 ul 30 ul
Kategorie	Metabolism Diabetes Glucose Homeostasis Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IHC
Clon	EGE-1
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Sensitivity	>5000 cells
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Beta-adrenergic receptor kinase 1,Beta-ARK-1,2.7.11.15,G-protein coupled receptor kinase 2,ADRBK1,BARK,BARK1,GRK2
Lieferbar
Manufacturer - Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular weight	51 kDa
Calculated Molecular weight	79574 MW
Clonality	Monoclonal
Application Details	WB 1:500-2000 IHC 1:50-200
Gene Name	ADRBK1
Gene Full Name	Beta-adrenergic receptor kinase 1
Immunogen	A synthesized peptide derived from human GRK2
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	0.5mg/ml
Manufacturer - Research Category	G Protein Signaling, Neuroscience, Neurotransmission, Receptors / Channels, Signal Transduction, Signaling Pathway
Protein Name	Glycogen synthase kinase-3 beta (gsk3b)
Protein Function	Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.
Subcellular Localization	Cytoplasm. Cell membrane.
Description	Boster Bio Anti-GRK2 ADRBK1 Rabbit Monoclonal Antibody catalog # M01473. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity	Expressed in peripheral blood leukocytes.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

BOS-M01473-datasheet.pdf

BOS-M01473-safety-datasheet.pdf