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Anti-Hexokinase 1 HK1 Rabbit Monoclonal Antibody Europäischer Partner

ArtNr BOS-M01504
Hersteller Boster
Menge 100 ul
Quantity options 100 ul 30 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, FC, IF, IHC, ICC
Clon EOF-8
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Sensitivity <20 pg/ml
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Hexokinase-1,2.7.1.1,Brain form hexokinase,Hexokinase type I,HK I,HK1
Lieferbar
Manufacturer - Category
Primary Antibodies, Rabbit Monoclonal Antibodies
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular weight
43 kDa
Calculated Molecular weight
102486 MW
Clonality
Monoclonal
Application Details
WB 1:500-2000
IHC 1:50-200
ICC/IF 1:50-200
FC 1:50
Gene Name
HK1
Gene Full Name
Hexokinase-1
Immunogen
A synthesized peptide derived from human Hexokinase 1
Contents
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Purification
Affinity-chromatography
Reconstitution
Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration
0.5mg/ml
Manufacturer - Research Category
T Lymphocytic Lineage
Protein Name
Glycogen synthase kinase-3 beta (gsk3b)
Protein Function
G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G (i) subclass of heteromeric G proteins. Signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. Plays an important role in cell migration, probably via its role in the reorganization of the actin cytoskeleton and the formation of lamellipodia in response to stimuli that increase the activity of the sphingosine kinase SPHK1. Required for normal chemotaxis toward sphingosine 1-phosphate. Required for normal embryonic heart development and normal cardiac morphogenesis. Plays an important role in the regulation of sprouting angiogenesis and vascular maturation. Inhibits sprouting angiogenesis to prevent excessive sprouting during blood vessel development. Required for normal egress of mature T-cells from the thymus into the blood stream and into peripheral lymphoid organs. Plays a role in the migration of osteoclast precursor cells, the regulation of bone mineralization and bone homeostasis (By similarity). Plays a role in responses to oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3- phosphocholine by pulmonary endothelial cells and in the protection against ventilator-induced lung injury.
Subcellular Localization
Mitochondrion outer membrane. Its hydrophobic N-terminal sequence may be involved in membrane binding.
Description
Boster Bio Anti-Hexokinase 1 HK1 Rabbit Monoclonal Antibody catalog # M01504. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Tissue Specificity
Isoform 2 is erythrocyte specific. Isoform 3 and isoform 4 are testis-specific.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 04.12.2025 

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