Anti-CLEC4E Antibody (Monoclonal, ABM42E6)

FACS, WB

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Monoclonal

CLEC4E

A full length human CLEC4E protein

Protein G Chromatography

Immunology, Innate Immunity, Macrophage/Inflammation

C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6, 6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.

Boster Bio Anti-CLEC4E Antibody (Monoclonal, ABM42E6) (Catalog# M06084). Tested in FACS, WB application(s). This antibody reacts with Human.