MECP2 Methyl CpG Binding Protein 2 Human Recombinant Protein

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Hersteller Boster
Kategorie
Typ Proteins Recombinant
Specific against other
Format Sterile Filtered colorless solution.
Menge 10ug
ArtNr BOS-PROTP51608
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Gene name
MECP2
Conjugate
No
Description
MECP2 Human Recombinant is expressed in 293 cells. The protein contains 486 amino acids (1-486a.a.) and fused to an N-terminal Flag tag, having an Mw of 53.56kDa.
Short description
MECP2 Human Recombinant is expressed in 293 cells. The protein contains 486 amino acids (1-486a.a.) and fused to an N-terminal Flag tag, having an Mw of 53.56kDa.
Uniprot ID
P51608
Purification
Greater than 80% as determined by SDS-PAGE.
Storage
Store in -20° C for long term storage. After reconstitution, store in 4° C for short term usage within a few days. Avoid freeze-thaw cycles.
Synonyms
Methyl-CpG-binding protein 2; MeCp-2 protein; MeCp2; MECP2;
Protein function
Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
Subcellular localization
Nucleus. Colocalized with methyl-CpG in the genome.
Tissue specificity
Present in all adult somatic tissues tested.
Source
Mammalian system, 293 cells.
Shipping
Shipped with wet ice

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Menge: 10ug
Lieferbar: In stock
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