Vergleich

MECP2 Methyl CpG Binding Protein 2 Human Recombinant Protein

Hersteller Boster
Kategorie
Typ Proteins Recombinant
Specific against other
Format Solution
Menge 10ug
ArtNr BOS-PROTP51608
Targets MECP2
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Description
MECP2 Human Recombinant is expressed in 293 cells. The protein contains 486 amino acids (1-486a.a.) and fused to an N-terminal Flag tag, having an Mw of 53.56kDa.
Gene name
MECP2
Protein function
Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
Purification
Greater than 80% as determined by SDS-PAGE.
Shipping
Shipped with wet ice
Short description
MECP2 Human Recombinant is expressed in 293 cells. The protein contains 486 amino acids (1-486a.a.) and fused to an N-terminal Flag tag, having an Mw of 53.56kDa.
Storage
Store in -20° C for long term storage. After reconstitution, store in 4° C for short term usage within a few days. Avoid freeze-thaw cycles.
Subcellular localization
Nucleus. Colocalized with methyl-CpG in the genome.
Tissue specificity
Present in all adult somatic tissues tested.
Format Information
Sterile Filtered colorless solution.

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Menge: 10ug
Lieferbar: Out of stock
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